Arizona Desert Centipede

S. heros is found in northern Mexico and the southwestern United States, from New Mexico and Arizona in the west to Arkansas, Missouri, and Louisiana in the east. Although this species is commonly referred to as the "giant desert centipede" because of its presence in the Sonoran and Chihuahuan Deserts, and other arid and semi-arid habitats, S. heros is also found in rocky woodland areas, such as in Arkansas.

S. heros is primarily a nocturnal predator and hunts invertebrates and small vertebrates, including rodents, reptiles, and amphibians. It is capable of reaching into the air to grab small flying insects. The centipede uses its venom to subdue prey.

S. heros hatch from eggs. As they grow and mature, like all arthropods they shed and molt away their exoskeleton. Each time they molt they enter a new stage of its life cycle called an instar. Like all Scolopendromorph centipedes, the number of segments they possess remains the same throughout their life. S. heros is a slow-growing species capable of living over a decade.

The venom of S. heros is similar in composition to the venom of other Scolopendra species, including components such as serotonin, histamine, lipids, proteins (including cardiotoxic proteins and enzymes such as hemolytic phospholipase A), and other substances. The mixture is known to act as a cytolysin, compromising cellular membranes and rupturing cells. S. heros venom also contains toxins targeted to its prey: one toxin numbs the nervous system of insects, rendering them unable to sense or escape, while another toxin interferes with the autonomic nervous system of vertebrates to make small vertebrates easier to subdue and devour. The exact effects and makeup of the venom have not been thoroughly evaluated, in part because it is difficult to extract in significant quantities and quickly deteriorates when processed. For humans, a bite from S. heros usually causes sharp, searing, local pain and swelling, but has never caused any confirmed deaths. S. heros bites are known to occasionally cause nausea, headache, and localized skin necrosis. However, there are individual cases of severe symptoms and injury (including kidney failure due to rhabdomyolysis, and heart attack) in humans resulting from Scolopendra bites.